- GeneralGeneral: Manganese deficiency may lead to digestive system diseases (520).
- AntacidsAntacids: According to secondary sources, antacids may interfere with manganese absorption.
- Calcium saltsCalcium salts: The addition of calcium to human milk significantly decreased manganese absorption (481).
- FatFat: In human research, low-fat diets inhibited the absorption of manganese (504).
- IronIron: In young sportsmen, iron-containing supplements decreased plasma manganese concentrations (521).
- MineralsMinerals: According to secondary sources, high intakes of magnesium, calcium, phosphorus, iron, copper, and zinc may inhibit the absorption of manganese.
- Phytic acidPhytic acid: According to secondary sources, phytic acid may inhibit the absorption of manganese (499).
- Ursodeoxycholic acid therapy (UDCA)Ursodeoxycholic acid therapy (UDCA): In patients with intrahepatic cholestatic liver disease, UDCA produced a significant decrease in manganese levels (522).
- VitaminsVitamins: The addition of vitamins (ascorutin, thiamin, riboflavin, pyridoxine, cyanocobalamin, and folic acid) to the diet may result in an increase in intestinal and urinary excretion of manganese (523).
- ZincZinc: According to secondary sources, high doses of manganese may inhibit the absorption of zinc. Zinc may affect manganese tissue levels (503).
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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.